Hematology Research Unit
         
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The group is involved in investigator initiated basic and clinical research in the areas of iron deficiency/iron overload, sickle cell disease, thalassaemia, and platelet disorders.
Major areas of research include characterization of anemia in children, development of novel assays to better define iron deficiency anemia and iron overload, and develop novel nutritional interventions to combat iron deficiency anemia. The studies are funded by peer reviewed grants obtained from National funding agencies including the Department of Biotechnology, Department of Science and Technology and the Indian Council of Medical Research and overseas foundations. In addition, faculty members are also involved in industry sponsored trials in the clinical area of lymphoma, leukemia and thrombocytopenia.

Current areas of investigation:

Biomarkers of iron deficiency and iron overload: The study is funded by the Department of Biotechnology, government of India. The study is coordinated by Ms.Sneha Pinto MSc.
Development of novel methods of food based iron fortification and assessment of their toxicity using proteomic strategies. This study is being performed in collaboration with the Jawahar Lal Nehru center for Advanced Scientific Research, Bangalore and is funded by the Nanomission, Ministry of Science and Technology, Government of India. The study is coordinated by Dr. Gopa PhD Dr. Gupta MD, Ms. Arpana MSc and Mr. Mandal.
The Karnataka Anemia project: Assessing the etiology of anemia in young children in rural Karnataka: The current project will determine the etiology of anemia in children aged 1-2 years in 2 rural districts of Karnataka. The project is in collaboration with the University of Melbourne and the Karuna Trust and is coordinated in the field by Dr. Sant-Rayn Pascricha, M.B.B.S. The study is funded in part by a generous grant from the Allen Foundation Inc, USA to Dr. Arun Shet and by a Melbourne University Research Scholarship to Dr. Pasricha.
Screening of thalassaemia in urban populations: Thalassaemia contributes to a large extent of the burden of hemoglobin disorders in the country and the current project is evaluating the role of molecular testing using a population based screening strategy.
ITP and bone marrow examination: Idiopathic thrombocytopenic Purpura (ITP) is a common hematological condition among our hospital in patients. We are investigated the role of bone marrow examination in patients who are clinically suspected to have ITP.
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