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Unit/Division |
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Division of Clinical Trials, NHLBI – UH CoE, Bangalore |
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Research Interests |
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Phase 3 Clinical Trials, |
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Health Economics |
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Perioperative Ischemia |
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Prevention of Cardiovascular Disease through translation research and policy change |
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Degrees |
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MBBS 1997,St Johns Medical College |
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MD Pharmacology, 2004, Rajiv Gandhi university of Health Sciences |
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Currently pursuing “MSc Clinical Trials” from the University of London, International Programmes (Scholarship from IKP Centre for Technologies in Public Health) |
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Current Positions |
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Program Manager – NHLBI – UH GHI CoE, Bangalore, 2009 till date |
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Vice Chairman –NHLBI-GHI COMMUNITY HEALTH WORKER SUBCOMMITTEE - 2010 - 11 |
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Chief Clinical Monitor – GSK Funded PROMOTE study, 2010 - 12 |
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Steering Committee Member |
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1 |
Pfizer supported Preferred Research Center. |
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2 |
AMEND Program |
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3 |
WELLCOME Funded, TIPS 3 study |
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Ongoing Projects |
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Co PI – Vascular Events in noncardiac Surgery (VISION India) |
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Co PI – INTERSTROKE India |
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Co PI – INSPIRE Study |
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Co PI – SPREAD Study |
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Co PI – The Indian Polycap & Potassium (K) Study – TIPS K Trial |
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Co PI – RELY AF registry |
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Trial Manager – Heart Outcomes Prevention Study – 3 (HOPE 3), PREPARE study, RIVAL study, ARISTOTLE, ASPIRE, |
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Recent Publications |
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Co-Author |
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The Indian Polycap Study (TIPS). Effects of a polypill (Polycap) on risk factors in middle aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomized trial. Lancet 2009. Online March 30, 2009 |
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Xavier D, Pais P, Sigamani A, Pogue J, Afzal R, Yusuf S. The need to test the theories behind the Polypill: rationale behind the Indian Polycap Study. Nat Clin Pract Cardiovasc Med. 2008 Dec 23. |
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Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomized controlled trial. POISE Study Group, The Lancet, Volume 371, Issue 9627, Pages 1839 - 1847, 31 May 2008 |
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Rationale, design, and organization of the PeriOperative Ischemic Evaluation (POISE) Trial: A randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery The POISE Trial Investigators - American Heart Journal August 2006 |
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Teaching / Presentations / Guest Lectures |
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Assistant Professor, Department of Pharmacology, St John’s Medical College, Bangalore |
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Research Faculty – NHLBI funded Health Research Methodology Workshop |
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Poster Presentation: Annual Meeting of the American Academy of Neurology in Seattle- WA , titled “PROFILE OF PHARMACOTHERAPY AND PHARMACOECONOMICS OF EPILEPSY TREATMENT AT A TERTIARY CARE HOSPITAL”., June 2009 |
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Guest Lecture – Recombinant Technology and Cytokines. MES Medical College, Perinthalmana, Kerala, July 2010 |
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Guest Speaker: Polypill: Is it an oversimplification? |
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ISMICS Winter Workshop & Cardiology Summit 2009 |
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