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Personnel:Research - Personal - Amit Kumar Mandal |
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Amit Kumar Mandal
Associate Professor- Molecular Medicine and Clinical Proteomics |
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Unit/Division |
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Molecular Medicine and Clinical Proteomics |
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Degrees |
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Ph.D. in Biophysical Chemistry, Bose Institute, Calcutta
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M.Sc. in Pure Chemistry with Physical Chemistry Specialization, University of Calcutta |
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B.Sc. in Chemistry Honours, University of Calcutta |
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Research Interests |
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Understanding structure function relationship of hemoglobin variants |
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Clinical proteome profile under different diseased states |
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Drug discovery from various of natural sources |
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Structural biology of protein nucleic acid interaction and protein folding |
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Awards & Certifications |
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Award of Research fellow from Council of Scientific and Induatrial Research, Govt. of India |
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Recent Publications |
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Electrospray mass spectrometric characterization of hemoglobin Q (Hb Q-India) and a double mutant hemoglobin S/D in clinical samples.
Clinical Biochemistry, 2008,41,75-81.
Amit Kumar Mandal, Shveta Bisht, Vijay Bhat, Patnam R Krishnaswamy, Padmanabhan Balaram. |
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Mass spectrometric identification of pyroglutamic acid in peptides following selective hydrolysis.
Analytical Biochemistry, 2007, 370, 118-120.
Amit Kumar Mandal, Padmanabhan Balaram. |
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Quantitation and characterization of glutathionyl hemoglobin as an oxidative stress marker in chronic renal failure by mass spectrometry.
Clinical Bichemistry, 20087,40,986-994.
Amit Kumar Mandal, Murali Woodi, Varun Sood, Patanam R Krishnaswamy, Anjali Rao, Sudarshan Ballal, Padmanabhan Balaram. |
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Sequencing of T-superfamily Conotoxins from Conus virgo: Pyroglutamic
acid Identification and Disulfide Arrangement by MALDI Mass Spectrometry
Amit Kumar Mandal, Mani Santhana Ramasamy, V. Sabareesh, Matthew E.
Openshaw, K.S. Krishnan, Padmanabhan Balaram.
Journal of the American Society for Mass Spectrometry, 2007,18,1396-1404. |
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Solvation Dynamics of a Protein in the Pre Molten Globule State.
J. Phys. Chem. B., 2006, 110, 21210-21215
Soma Samaddar, Amit Kumar Mandal, Sudip Kumar Mondal, Kalyanasis, Sahu, Kankan Bhattacharyya, Siddhartha Roy. |
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Glutamate counteracts the denaturing effect of urea through its effect on the denatured State.
J. Biol.Chem, 2003, 278, 36077-36084.
Amit Kumar Mandal, Soma Samaddar, Rajat Banerjee, Simanti Lahiri, Anusree Bhattacharyya and Siddhartha Roy. |
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Solvation change and ion release during aminoacylation by aminoacyl-tRNA synthetases.
Nucleic Acids Research, 2003, 31, 6035-6042
Rajat Banerjee, Amit Kumar Mandal, Rajesh Saha, Soumi Guha, Soma Somaddar, Anusree Bhattacharyya and Siddhartha Roy |
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Solvation Dynamics of a Probe Covalently Bound to a Protein and in an AOT
Microemulsion: 4-(N-Bromoacetylamino)-Phthalimide.
J. Phys. Chem. B, 2002, 106, 10741-10747.
Debabrata Mandal, Sobhan Sen, Dipankar Sukul and Kankan Bhattacharyya
Amit Kumar Mandal, Rajat Banerjee and Siddhartha Roy. |
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Dynamics of compact denatured states of glutaminyl-tRNA synthetase probed by bis-ANS binding kinetics.
Biophysical Chem, 2000, 87, 201-212.
Anusree Bhattacharyya, Amit Kumar Mandal, Rajat Banerjee, Siddhartha Roy. |
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A cognate tRNA specific conformational change in glutaminyl-tRNA synthetase and its implication for specificity.
Protein Science, 1998, 7, 1046-1051.
Amit Kumar Mandal, Anusree Bhattacharyya, Subhra Bhattacharyya, Tista
Bhattacharyya and Siddhartha Roy. |
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